ABSTRACT
BACKGROUND: Recent studies report that nursing home elderly (NHE) have significantly lower serum levels of 25-hydroxy-vitamin D (25-OHD) than community dwelling elderly (CDE); however, in Korea such studies are lacking. We aimed to compare the vitamin D status between NHE and CDE in Korea. METHODS: This study included 203 patients over 65 years, admitted to the geriatric department of Seoul Medical Center between 01/2015 and 12/2015. Their medical records were reviewed for demographic data, type of residence, medical and drug history, serum 25-OHD, albumin, creatinine, and calcium levels, and geriatric assessment results. After excluding 36 subjects who had taken vitamin D supplements, anticonvulsants, or steroids, 33 NHE and 134 CDE were included for final analysis. RESULTS: Almost 80% of subjects showed a vitamin D deficiency (25-OHD <20 ng/mL); 54% were severely deficient (25-OHD <10 ng/mL). NHE had a significantly lower serum 25-OHD level than CDE (5.47±2.95 ng/mL vs. 14.72±11.35 ng/mL, p<0.001). Serum 25-OHD level was related to serum albumin level, the Geriatric Depression Scale score, and the Korean version of the Mini Mental State Examination score (p=0.004, p=0.041, p=0.032, respectively). After adjustment for confounding factors using multiple logistic regression analysis, diagnosis of severe vitamin D deficiency was more likely in NHE than CDE (odds ratio, 8.72; 95% confidence interval, 1.53-49.81). CONCLUSION: This study suggests a high prevalence of vitamin D deficiency in Korean NHE. To prevent falls and osteoporotic fractures in this population, vitamin D supplementation should be considered.
Subject(s)
Aged , Humans , Accidental Falls , Anticonvulsants , Calcium , Creatinine , Depression , Diagnosis , Geriatric Assessment , Independent Living , Korea , Logistic Models , Medical Records , Nursing Homes , Nursing , Osteoporosis , Osteoporotic Fractures , Prevalence , Seoul , Serum Albumin , Steroids , Vitamin D Deficiency , Vitamin D , VitaminsABSTRACT
Mucormycosis is a rare and fulminating opportunistic fungal infection that occurs almost in immunocom-promised patients. It is also a highly virulent and rapidly progressive disease with poor prognosis. Its incidence has been increasing in recent years. We have experienced a case of solitary duodenal mucormycosis in a 45 year-old male patient. Mucormycosis was diagnosed by pathology & culture and he was treated with amphotericin B and discharged with clinical improvement. We report this case with a literature review.